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Dr. Maddika Subba Reddy
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Home » Cell Death & Cell Survival » Publications
Cell Death & Cell Survival
  1. A human tyrosine phosphatase interactome mapped by proteomic profiling P Kumar, P Munnangi, KVSR Chowdary, VJ Shah. - Journal of Proteome ., 2017 Tyrosine phosphatases play critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in cell is limited. By utilizing proteomic approach, here we present an interaction network of 81 human tyrosine

  2. Maddika S@., Kavela S., Rani M., Palicharla VR and Chen J@. WWP2 is an E3 ubiquitin ligase for PTEN. Nature Cell Biol 2011 (In press) [@Equal corresponding author].

  3. Maddika S and Chen J. Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3-ligase. Nature Cell Biol 2009; 11(4):409-19.

  4. Maddika S., Sy SM and Chen J. Functional interaction between Chfr and Kif22 controls genomic stability. J Biol Chem. 2009; 284(19):12998-3003.

  5. Ande SR., Chen J and Maddika S@. The ubiquitin pathway: An emerging drug target in cancer therapy. Eur J Pharmacol. 2009; 625(1-3):199-205. [@ Corresponding author]

  6. Maddika S., Panigrahi S., Weichec E., Wesselborg S., Fischer U., Schulze-Osthoff K and Los M. Unscheduled Akt- triggered activation of CDK2 as a key effector mechanism of apoptin’s anti-cancer toxicity. Mol Cell Biol. 2009; 29(5): 1235-48.

  7. Los M., Maddika S and Schulze-Osthoff K. Switching Akt: From survival signaling to deadly response. BioEssays 2009; 31(5):492-5.

  8. Ghavami S, Eshraghi M, Kadkhoda K, Mutawe MM, Maddika S, Bay GH, Wesselborg S, Halayko AJ, Klonisch T and Los M. Role of BNIP3 in TNF-induced cell death--TNF upregulates BNIP3 expression. Biochim Biophys Acta. Mol Cell Research 2009; 1793(3):546-60.

  9. Maddika S., Ande SR., Weichec E., Hansen LL., Wesselborg S and Los M. Akt mediated CDK2 phosphorylation regulates its dual role in cell cycle and apoptosis. Journal of Cell Sci. 2008, 121 (7): 979-88.

  10. Maddika S., Weichec E., Ande SR., Poon IK., Fischer U., Wesselborg S., Jans DA., Schulze-Osthoff K and Los M. Interaction with PI3-Kinase contribute to the cytotoxic activity of apoptin. Oncogene 2008, 27 (21): 3060-5.

  11. Maddika S., Bay GH., Kroczak TZ., Ande SR., Maddika S., Weichec E., Gibson SB and Los M. Akt is transferred to the nucleus of cells treated with apoptin, and it participates in apoptin induced cell death. Cell Proliferation 2007, 40 (6): 435-48.

  12. Maddika S., Ande SR., Panigrahi S., Paranjothy T., Weglarczyk K., Zuse A., Eshraghi M., Manda KD., Wiechec E and Los M. Cell survival, cell death and cell cycle pathways are interconnected. Drug Resist Updates 2007, 10 (1-2) 13-29.

  13. Maddika S., Mendoza FJ., Hauff K., Zamzow CR., Paranjothy T and Los M. Cancer Selective Therapy of the Future: Apoptin and Its Mechanism of Action. Cancer Biol Ther. 2006 Vol 5(1): 10-19.

  14. Kroczak TJ., Baran J., Pryjma J., Siedlar M., Reshedi I., Hernandez E., Alberti E., Maddika S., and Los M. The emerging importance of DNA mapping and other genome based techniques as tools to identify new drug targets and as a mean of therapy personalization. Expert Opin. Ther. Targets 2006: Vol 10(2): 289-302.

  15. Burek M#., Maddika S#., Burek CJ., Daniel PT., Schulze-Osthoff K., and Los M. Apoptin induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent. Oncogene 2006. 25(15): 2213-22. [# Equal First Authorship]

  16. Maddika S., Booy EP., Johar D., Gibson SB., Ghavami S., and Los M. Tumor-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell death mediators by a Nur77 dependent pathway. Journal of Cell Sci. 2005, 118 (19): 4485 – 4493.

  17. Hashemi M., Karami-Tehrani F., Ghavami S., Maddika S., and Los M. Adenosine and Deoxyadenosine induces apoptosis in the estrogen receptor positive and negative human breast cancer cells via the intrinsic pathway. Cell proliferation 2005, 38 (5): 269-85.

  18. Barczyk K., Kreuter M., Pryjma J., Booy EP., Maddika S., Ghavami S., Berdel WE., Roth J., and Los M. Serum cytochrome c indicates invivo apoptosis and can serve as a prognostic marker during cancer therapy. Int J Cancer 2005; 116(2); 167-73.

  19. Kreuter M., Langer C. Kerkhoff C., Reddanna P., Kania A.L., Maddika S., Chlichlia K., Bui NT., and Los M (2004) Stroke, myocardial infarct, acute and chronic inflammatory diseases: Caspases and other apoptotic molecules as targets for drug development. Arch. Immunol. Ther. Exp. 2004,Vol 52, 141-155.

List of book chapters:
  1. Ghavami S., Barczyk K., Maddika S., Pourjafari H., Kroczak T., and Los, M. Monitoring of programmed cell death in vivo: new methods of cancer therapy monitoring. In: Apoptotic pathways as target for novel therapies in cancer and other diseases. Edited by M. Los & S.B Gibson; Kluwer Academic Press, (2004), ISBN 0-387-23384-9.

  2. Banerji S., Ande SR., Maddika S., Banerji V., Rashedi I., Owens NW., Zuse A., Schweizer F. and Los M.“Peptides and peptidomimetics as cancer therapy sensitizing agents” in: Sensitization of Cancer Cells to Chemo/Immuno/Radio Therapy. (2008) edited by: B. Bonavida; Humana Press, Inc. ISBN 934115290.
Contact Information
Email: msreddy<at>cdfd.org.in
Phone: +91-40-24749353 / 358
Fax: +91-40-24749448
Last updated on: Tuesday, 18thJuly, 2017.

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