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Dr. P. Govindaraj
Awards, Fellowships & Honours
Home » Human Molecular Genetics
Human Molecular Genetics
Research interests:

Last decade of biomedical research, there has been a remarkable convergence of interest in the powerhouse of cells, the mitochondria. Mitochondrial dysfunction is associated with a broad spectrum of human disorders, ranging from rare, inborn errors of metabolisms to common, age-related conditions, including cardiovascular and neurodegenerative diseases. However, the emerging field of mitochondrial medicine is hindered by the complexity of these organelles and breadth of implication in disorders, leading to a lack of mechanistic insights, biomarker discovery, and therapeutic targets.

The long-term goals of our group are to explore the new genes that are associated with mitochondrial disorders, understand the molecular mechanisms, and develop theragnostics (diagnosis and treatment).

Current projects:

  • Investigating the interaction between mtDNA and nDNA using next-generation sequencing.
  • Multi-omics approach to understand mitochondrial disorders
  • Delineate the molecular mechanism leading to neuronal loss and neurological defects in mitochondrial disorders.
  • In addition, we are also interested in identifying the novel genetic cause and functional characterization using cellular models of other rare genetic disorders.

    Contact Information
    Email: govind<at>cdfd.org.in
    Phone: +91-40-27216121
    Fax: +91-40- 27216006
    Last updated on: Tuesday, 13th July, 2021

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