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Dr. Akash Ranjan
Research
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Home » Computational & Functional Genomics » Research
Computational & Functional Genomics
"We harness the synergy of computing and experiments to address challenges in biology"
- Akash Ranjan
We study genomic encoding of molecular mechanisms and circuits that control cellular functions in physiology and pathology. We have developed many computational and experimental approaches to unravel genomic encoding of physiological function. We are currently applying these approaches to study the physiology and pathology associated with bacterial pathogens (such as pathogenic E.coli and M. tuberculosis), apicomplexan parasites (such as Plasmodia etc.) and humans. Under this theme, we are working on:
  • Study of amino acid substitution pattern in apicomplexan parasites and its impact on improving genome annotations and functional characterization.
  • Structural and functional studies of P. falciparum proteins associated with parasite physiology and human pathology.
  • Role of small non-coding RNA in Plasmodium biology.
  • Implementation and assessment of genomic context based methods to propose functional tag for genome encoded proteins.
  • Functional characterization of transcription initiation regulators and their regulons in physiology and pathology.
  • Physiological machinery for sensing and modulation of proteins aggregation in human cells.

Research at our group is currently supported by funds from Department of Biotechnology, Government of India.
How to join this group
Contact Information
Email: akash<at>cdfd.org.in
Phone: +91-40-24749395
Fax: +91-40-24749448
Last updated on: Wednesday, 24th August, 2016

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