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"SEMINAR"
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"Fat, Fertility and Immunity in an Aging Worm"
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by
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Dr Arjumand Ghazi
Associate ProfessorUniv. of Pittsburg, USA
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20 August, 2018 12:00 noon
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at CDFD Lecture Hall, 3rd Floor, Lab Building.
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Abstract:
My lab uses C. elegans to study genes that coordinate the dialogue between the reproductive system and aging pathways.
To understand the molecular underpinning of this complex and dynamic relationship, we have used as molecular tools a group of
pro-longevity transcription factors, DAF-16/FOXO3A, TCER-1/TCERG1 and NHR-49/PPARa. Our studies have revealed that these proteins
impact lipid homeostasis, innate immunity and stress-response pathways to translate signals from germ cells into physiological
changes in lifespan and healthspan. I will discuss some of our recent discoveries in this area.
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