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Dr. Prem S. Kaushal


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Research Publications


Research Publications

  1. Qu G *, Kaushal PS*, Wang J*, Shigematsu H, Piazza CL, Agrawal RK, Belfort M & Wang HW. Structure of group II intron complexed with its transcriptase. (2016) Nature Structure and Molecular Biology (NSMB) 23, 549-57. (*equal contributions). Highlighted as the News and Views in NSMB 23, 507-9 and a follow up review in RNA BIOLOGY 13, 1218-22.

  2. Kaushal PS*, Sharma MR*, Booth TM, Haque E, Tung C, Sanbonmatsu KY, Spremulli LL and Agrawal R K. (2014) Cryo-EM structure of the small subunit of the mammalian mitochondrial ribosome. Proceedings of the National Academy of Sciences USA (PNAS) 111(20), 7284-9 (*equal contributions).

  3. Ahmad MF, Kaushal PS, Wan, Q, Wijeratna SR, An X, Huang M & Dealwis CD. (2012) Role of arginine-293 and glutamine-288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. Journal of Molecular Biology 419, 315-29.

  4. Kaushal PS, Singh P, Sharma A, Muniyappa K & Vijayan M. (2010) X-ray and molecular dynamics studies on Mycobacterium leprae single-stranded DNA binding protein and comparison with other eubacterial SSB structures. Acta Crystallographica D66, 1048-58.

  5. Kaushal PS, Talawar RK, Varshney U & Vijayan M. (2010) Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis. Insights into interactions with ligands. Acta Crystallographica F66, 887-92 (cover illustration).

  6. Kaushal PS, Talawar RK, Krishna PD, Varshney U & Vijayan M. (2008). Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources. Acta Crystallographica D64, 551-560.

  7. Kaushal PS, Sankaranarayanan R & Vijayan M. (2008) Water-mediated variability in the structure of relaxed-state haemoglobin. Acta Crystallographica F64, 463-9.

  8. Singh P, Talawar RK, Krishna PD, Varshney U & Vijayan M. (2006) Overexpression, purification, crystallization and preliminary X-ray analysis of uracil N-glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor. Acta Crystallographica F62, 1231-4.

  • Kaushal PS, Sharma MR and Agrawal RK. (2015) The 55S mammalian mitochondrial ribosome and its tRNA-exit region. Biochimie. 114, 119-26.

  • Wijerathna SR, Ahmad MF, Xu H, Fairman JW, Zhang A, Kaushal PS, Wan Q, Kiser J & Dealwis CG. (2011) Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy. Pharmaceuticals, 4(10),1328-54.

    Book chapters
    1. Sharma MR, Kaushal PS, Gupta M, Banavali N K, & Agrawal RK. (2013) Insights into structural basis of mammalian mitochondrial translation. In Translation in Mitochondria and Other Organelles, Duchene, A.M. ed. (Springer-Verlag, Berlin/ Heidelberg), pp. 1-28, DOI: 10.1007/978-3-642-39426-3_1.
    2. Kaushal PS, Wan Q, Faber C, & Dealwis C. (2012) Crystal dehydration Technique. In Crystallography: Research, Technology and Applications, Hokkaido, M. and Nagano, E. ed. (Nova Science Publishers, Inc.), pp. 91-104, ISBN:978-1-62081-574-8.

    Contact Information
    Email : kaushal@cdfd.org.in
    Phone : +91-40-27216105
    Fax : +91-40- 27216006
    Last updated on : Tuesday, 5th June, 2018.

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